{"id":166562,"date":"2023-07-31T12:43:17","date_gmt":"2023-07-31T10:43:17","guid":{"rendered":"https:\/\/www.sggw.edu.pl\/?p=166562"},"modified":"2023-07-31T12:44:23","modified_gmt":"2023-07-31T10:44:23","slug":"the-antibiotic-resistance-sggw-scientists-struggle-with-the-global-challenge","status":"publish","type":"post","link":"https:\/\/www.sggw.edu.pl\/en\/the-antibiotic-resistance-sggw-scientists-struggle-with-the-global-challenge\/","title":{"rendered":"The Antibiotic Resistance – SGGW scientists struggle with the global challenge"},"content":{"rendered":"\t\t
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\n The Antibiotic Resistance – SGGW scientists struggle with the global challenge\n <\/h1>\n <\/div>\n <\/section>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\u2013 PhageLand \u2013<\/span><\/p>

Antibiotic Resistance – the global issue<\/span><\/p>

The prevalence of antibiotic resistance has become a global problem and a real threat to public health. Municipal wastewater was identified as a possible source of antibiotic-resistant bacteria and antibiotic-resistance genes spreading over other environments. Therefore, new, low-cost and eco-friendly technologies are needed to purify wastewater from antibiotics, antibiotic-resistant bacteria and antibiotic-resistance genes.<\/span><\/p>

The main target – an innovative strategy<\/span><\/p>

Phageland project aims to develop a novel intervention strategy to prevent the transmission of antibiotic resistance from wastewater into surface waters.\u00a0<\/span>The prevalence of antibiotic resistance has become a global problem and a real threat to public health, says Dr Ma\u0142gorzata Grzesiuk-Bieniek<\/strong>, Department of Biochemistry and Microbiology, Institute of Biology, SGGW.\u00a0<\/span>We need new, low-cost, and eco-friendly technologies to purify wastewater from antibiotics, antibiotic-resistant bacteria and antibiotic-resistance genes.<\/span><\/p>

PhageLand includes public health investigations targeting multidrug-resistant bacterial (ARB) pathogens in low-middle income countries (LMICs) in Eastern Europe. The phage-based treatment will be specifically tailored to eliminate these multidrug-resistant pathogens from wastewater.\u00a0<\/span>In parallel, PhageLand aims to assess: a) the self-purification capacity of model full-scale CWs operating in Spain and Moldova in removing antibiotic residues, ARB and antibiotic resistance genes (ARGs); and b) the potential risk associated with the dissemination of ARB and ARGs within indigenous bacterial communities and among animals inhabiting CWs.<\/span><\/p>

The Method<\/span><\/p>

Experimental tasks will include field and laboratory experiments i<\/span>nvolving cutting-edge chemical, biotechnological and (meta)genomic techniques as well as animal testing. <\/span>Finally, a pilot-scale infrastructure will be used to scale up the PhageLand technology and to assess its performance under real environmental conditions. This proof-of-concept will be used to demonstrate the efficacy and scalability of this nature-based technology for combating AR and to encourage stakeholders for its implementation in wastewater treatment, particularly in LMICs where costly and power-demanding treatment plants are difficult to set up.<\/span><\/p>\n <\/div>\n <\/div>\n <\/section>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

The Antibiotic Resistance – SGGW scientists struggle with the global challenge \u2013 PhageLand \u2013 Antibiotic Resistance – the global issue The prevalence of antibiotic resistance has become a global problem and a real threat to public health. Municipal wastewater was identified as a possible source of antibiotic-resistant bacteria and antibiotic-resistance genes spreading over other environments. […]<\/p>\n","protected":false},"author":21,"featured_media":166539,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[133],"tags":[],"class_list":["post-166562","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.sggw.edu.pl\/en\/wp-json\/wp\/v2\/posts\/166562","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sggw.edu.pl\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.sggw.edu.pl\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.sggw.edu.pl\/en\/wp-json\/wp\/v2\/users\/21"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sggw.edu.pl\/en\/wp-json\/wp\/v2\/comments?post=166562"}],"version-history":[{"count":8,"href":"https:\/\/www.sggw.edu.pl\/en\/wp-json\/wp\/v2\/posts\/166562\/revisions"}],"predecessor-version":[{"id":166570,"href":"https:\/\/www.sggw.edu.pl\/en\/wp-json\/wp\/v2\/posts\/166562\/revisions\/166570"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.sggw.edu.pl\/en\/wp-json\/wp\/v2\/media\/166539"}],"wp:attachment":[{"href":"https:\/\/www.sggw.edu.pl\/en\/wp-json\/wp\/v2\/media?parent=166562"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.sggw.edu.pl\/en\/wp-json\/wp\/v2\/categories?post=166562"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.sggw.edu.pl\/en\/wp-json\/wp\/v2\/tags?post=166562"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}